PAVLIDES, Constantine

Title Professor
Degree Ph.D
Division Psychology
Research Field Neuroscience, Neurophysiology
Undergraduate Program College of Psychology
Graduate School Program (Main) Doctral Program for Kansei, Behavioral and Brain Sciences
Graduate School Program (Sub)
Research Themes

1. Hippocampal functional organization for the encoding of memory.

2. Mechanisms underlying memory consolidation in sleep.

Publications/Major Achievements
  • Pavlides, C. & Winson, J. Influences of hippocampal place cell firing in the awake state on the activity of these cells during subsequent sleep episodes. J Neurosci 9,2907–2918 (1989).
  • Iriki, A., Pavlides, C., Keller, A. & Asanuma, H. Long-term potentiation in the motor cortex. Science 245,1385–1387 (1989).
  • Iriki, A., Pavlides, C., Keller, A. & Asanuma, H. Long-term potentiation of thalamic input to the motor cortex induced by coactivation of thalamocortical and corticocortical afferents. J Neurophysiol 65,1435–1441 (1991).
  • Pavlides, C., Miyashita, E. & Asanuma, H. Projection from the sensory to the motor cortex is important in learning motor skills in the monkey. J Neurophysiol 70,733–741 (1993).
  • Pavlides, C., Ogawa, S., Kimura, A. & McEwen, B. S. Role of adrenal steroid mineralocorticoid and glucocorticoid receptors in long-term potentiation in the CA1 field of hippocampal slices. Brain Res 738,229–235 (1996).
  • Asanuma, H. & Pavlides, C. Neurobiological basis of motor learning in mammals. Neuroreport 8, i–vi (1997).
  • Pavlides, C. & McEwen, B. S. Effects of mineralocorticoid and glucocorticoid receptors on long-term potentiation in the CA3 hippocampal field. Brain Res 851, 204–214 (1999).
  • Ribeiro, S., Goyal, V., Mello, C. V. & Pavlides, C. Brain gene expression during REM sleep depends on prior waking experience. Learn Mem 6,500–508 (1999).
  • Kimura, A. & Pavlides, C. Long-term potentiation/depotentiation are accompanied by complex changes in spontaneous unit activity in the hippocampus. J Neurophysiol 84,1894–1906 (2000).
  • Ribeiro, S. et al.Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep. Journal of Neuroscience 22,10914–10923 (2002).
  • Yamada, K., McEwen, B. S. & Pavlides, C. Site and time dependent effects of acute stress on hippocampal long-term potentiation in freely behaving rats. Exp Brain Res 52,52–59 (2003).
  • Ishikawa, H., Yamada, K., Pavlides, C. & Ichitani, Y. Sleep deprivation impairs spontaneous object-place but not novel-object recognition in rats. Neurotic Lett 580,114–118 (2014).
  • Nakamura, N. H. et al.Hippocampal cells encode places by forming small anatomical clusters. Neuroscience 166,994–1007 (2010).
  • Cho, J. et al.Fear memory consolidation in sleep requires protein kinase A. Learn Mem 25,241–246 (2018).
  • Pavlides, C. et al.Hippocampal functional organization: A microstructure of the place cell network encoding space. Neurobiol Learn Mem 161,122–134 (2019).
Scientific Membership

Society for Neuroscience, USA.

Japan Society for Neuroscience.

Social and Outreach Activity
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