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教員紹介

教員紹介

Constantine PavlidesConstantine Pavlides

所属 人間系
職名 教授
学位 Ph.D
メールアドレス
HPアドレス  
研究領域 実験心理学
専門分野 Neuroscience, Neurophysiology, Electrophysiology
担当 人間学群心理学類
人間総合科学研究科感性認知脳科学専攻
研究テーマ Neuronal Plasticity; Learning and Memory; Sleep; Hippocampal Function
主要業績
  • Iriki, A., Pavlides, C., Keller, A. and Asanuma, H. (1989). Long-term potentiation in the motor cortex. Science, 245, 1385-1387.
  • Pavlides, C. and Winson, J. (1989). Influences of hippocampal place cell firing in the awake state on the activity of these cells during subsequent sleep episodes. J Neurosci, 9, 2907-2918.
  • Iriki, A., Pavlides, C., Keller, A. and Asanuma, H. (1991). Long-term potentiation of thalamic input to the motor cortex induced by coactivation of thalamocortical and corticocortical afferents. J Neurophysiol, 65, 1435-1441.
  • Pavlides, C., Watanabe, Y. and McEwen, B.S. (1993). Effects of glucocorticoids on hippocampal long-term potentiation. Hippocampus, 3, 183-192.
  • Pavlides, C., Watanabe, Y., Magariños, A.M. and McEwen, B.S. (1995). Opposing roles of Type I and Type II adrenal steroid receptors in hippocampal long-term potentiation. Neuroscience, 68, 387-394.
  • Asanuma, H. and Pavlides, C. (1997). Neurobiological basis of motor learning in mammals. NeuroReport, 8 (3), i-vi.
  • Ribeiro, S. Goyal, V., Mello, C.V. and Pavlides, C. (1999). Brain gene expression during REM sleep depends on prior awake experience. Learn Mem,6(5), 500-508.
  • Pavlides, C., Miyashita, E. and Asanuma, H. (1993). Impairment in learning novel motor skills by lesion of the somatosensory cortex in the monkey. J Neurophysiol, 70, 773-741.
  • Kimura, A. and Pavlides, C. (2000). Long-term potentiation/depotentiation are accompanied by complex changes in spontaneous unit activity in the hippocampus. J Neurophysiol, 84, 1894-1906.
  • Sarnyai, Z., Etienne L. Sibille, E.L., Pavlides, C., Fenster, R.J., Dedesma, C., McEwen, B.S. and Toth, M. (2000). Increased limbic excitability and altered short-lasting neuroplasticity in the dentate gyrus are associated with hippocampal-dependent memory impairments in mice lacking 5HT-1A receptors. PNAS, 97, 14731-14736.
  • Pavlides, C., Nivón, L.G. and McEwen, B.S. (2002). Effects of chronic restraint stress on hippocampal long-term potentiation. Hippocampus, 12(2) 245-257.
  • Ribeiro, S., Mello, C.V. Velho, T., Gardner, T., Jarvis, E. and Pavlides, C. (2002). Induction of hippocampal long-term potentiation during waking leads to increased extrahippocampal zif-268 expression during ensuing rapid-eye-movement sleep. J Neurosci, 22, 10914-10923.
  • Yamada, K., McEwen, B.S. and Pavlides, C. (2003). Site- and time-dependent effects of acute stress on hippocampal long-term potentiation in freely behaving rats. Exp Brain Res,152, 52-59.
  • Matys, T., Pawlak, R. Matys, E., Pavlides, C., McEwen, BS, Strickland, S. (2004). Tissue plasminogen activator promotes the effects of corticotropin-releasing factor on the amygdala and anxiety-like behavior. PNAS, 101 (46), 16345-16350.
  • Romcy-Pereira, R. and Pavlides, C. (2004). Distinct modulatory effects of sleep on the maintenance of hippocampal and medial prefrontal cortex LTP. Eur J Neurosci, 20, 3453-3462.
  • Miwa, J. M., Stevens, T. R., King, S. L., Caldarone, B. J., Ibanez-Tallon, I., Xiao, C., Fitzsimonds, R. M., Pavlides, C., Lester, H. A., Picciotto, M. R. and Heintz, N., 2006. The Prototoxin lynx1 Acts on Nicotinic Acetylcholine Receptors to Balance Neuronal Activity and Survival In Vivo. Neuron. 51, 587-600.
  • Caria, M.A., Dratman, M.B. Kow, L.-M. Tavera, C., Mameli, O. and Pavlides, C. (2009). Thyroid hormone action: nongenomic modulation of neuronal excitability in the hippocampus. J. Neuroendocrinol. 21, 98-107.
  • Romcy-Pereira, R., Erraji-BenChekroun, L., Smyrniotopoulos, P., Sibille, E., Ogawa, S. Mello4, C., and Pavlides, C. (2009). Sleep-dependent Gene Expression changes in the Prefrontal Cortex following Hippocampal Long-Term Potentiation, Physiol Behav, 98, 44-52.
  • Goldwater, D.S., Pavlides, C., Hunter, R.G., Bloss, E.B., Hof, P.R., McEwen, B.S. and Morrison, J.H. (2009). Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery. Neuroscience, 164 (2), 798-808.
  • Nakamura, N.H., Fukunaga, M., Akama, K.T., Soga, T., Ogawa, S., Pavlides, C. (2010) Hippocampal cells encode places by forming small anatomical clusters. Neuroscience, 166:994-1007.
  • Martin, E.M., Pavlides, C. and Pfaff, D. (2010). Multi-modal sensory responses of nucleus reticularis gigantocellularis and the responses’ relation to cortical and motor activation. J Neurophysiol, 103 (5), 2326-2338.
  • Arrieta-Cruz, I., Wang, J., Pavlides, C. and Pasinetti, G.M. (2010). Carvedilol re-establishes long-term potentiation in a mouse model of Alzheimer’s disease. J Alzheimer’s Dis, 21 (2), 649-654.
  • Arrieta-Cruz, I., Pavlides, C. And Pasinetti, G.M. (2010). Deep brain stimulation in midline thalamic region facilitates synaptic transmission and short-term memory in a mouse model of Alzheimer’s disease. Translational Neurosci, 1(3), 188-194.
  • Carlson, K., Dhadialla, P.S., Feaster, M., Ramnaain, A., Pavlides, C., Chen, Z.L., Yu, W.-M., Feltri, M.L., and Strickland, S. (2011). Adipose-derived stem cells facilitate axon sorting and myelination in mice deficient in Schwann cell-derived laminin. Glia, 59 (2), 267-277.
  • Wang, j., Ferruzzi, M.G., Ho, L., Blount, J. W., Janle, E.,Gong , B., Pan, Y., Raftery, D., Arrieta-Cruz, I., Sharma, V., Cooper, B., Lobo, J., Simon, J., Cheng, A., Qian, X., Zhang, C., Ono, K., Teplow, D.B., Pavlides, C., Dixon, R.A. and Pasinetti, G.M. (2012). Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment, J Neurosci, 32(15), 5144-5150.
  • Ishikawa, H., Yamada, K, Pavlides, C. And Ichitani, Y. (2014). Sleep deprivation impairs spontaneous object-place but not object recognition in rats. Neurosci. Lett., 580, 114-118.
 
所属学会 Society for Neuroscience, USA.
Japanese Neuroscience Society, Japan.
社会的活動  

 

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