人間系心理学域TOP

研究領域とスタッフ

研究領域とスタッフ

高橋 阿貴Aki Takahashi

所属 人間系
職名 准教授
学位 博士(理学)
メールアドレス
HPアドレス http://www.kansei.tsukuba.ac.jp/~ogawalab/
研究領域 実験心理学
専門分野 行動神経科学、光遺伝学、行動遺伝学
担当 人間学群心理学類
人間総合科学研究科感性認知脳科学専攻
研究テーマ マウスを用いた攻撃行動の神経学的基礎の解析
主要業績
  • Takahashi A, Shiroishi T, Koide T (2014) Genetic mapping of escalated aggression in wild-derived mouse strain MSM/Ms: association with serotonin-related genes. Frontiers in Neuroscience. 8:156
  • Takahashi A, Nagayasu K, Nishitani N, Kaneko S, Koide T (2014) Control of intermale aggression by medial prefrontal cortex activation in the mouse. PLOS ONE. 9(4):e94657
  • Miyazaki KW, Miyazaki K, Tanaka KF, Yamanaka A, Takahashi A, Tabuchi S, Doya K (2014) Optogenetic activation of dorsal raphe serotonin neurons enhances patience for future rewards. Current Biology. 24(17):2033-2040.
  • Sluyter F, Takahashi A, Maxson SC (2014) Pathological aggression. In, Susanna Pietropaolo, Frans Sluyter and Wim E. Crusio (Eds), Behavioral Genetics of the Mouse Vol. 2: Genetic Mouse Model of Neurobehavioral Disorders (Chapter 10). Cambridge, UK: Cambridge University Press.
  • Kanno K, Kokubo H, Takahashi A, Koide T, Ishiura S (2014) Enhanced prepulse inhibition and low sensitivity to a dopamine agonist in HESR1 knockout mice. Journal of Neuroscience Research 92(3):287-297.
  • Arakawa T, Tanave A, Ikeuchi S, Takahashi A, Kakihara S, Kimura S, Sugimoto H, Asada N, Shiroishi T, Tomihara K, Tsuchiya T, Koide T (2014) A male-specific QTL for social interaction behavior in mice mapped with automated pattern detection by a hidden Markov model incorporated into newly developed freeware. Journal of Neuroscience Methods. 234: 127-134.
  • Takahashi A, Miczek KA (2014) Neurogenetics of aggressive behavior: Studies in rodents. In, Klaus Miczek and Andreas Meyer-Lindenberg (Eds), Current Topics in Behavioral Neurosciences. 17, pp. 3-44. Heidelberg: Springer.
  • 高橋阿貴、小出剛 (2013) 系統について知ろう(第2章)、マウスの行動を解析しよう(第10章) 小出剛(編)「マウス実験の基礎知識 第2版」オーム社
  • Takahashi A, Schilit AN, Kim J, DeBold JF, Koide T, Miczek KA (2012) Behavioral characterization of escalated aggression induced by GABAB receptor activation in the dorsal raphé nucleus. Psychopharmacology (Berl). 224(1):155-166.
  • 高橋阿貴 (2012) 光遺伝学(オプトジェネティクス):行動を制御する神経回路をあきらかにする試み 動物心理学研究. 総説. 62(2), 147-162.
  • Takahashi A, Quadros IM, de Almeida RM, Miczek KA. (2012) Behavioral and pharmacogenetics of aggressive behavior. In, John Cryan (Ed), Current Topics in Behavoral Neurosciences. 12, pp 73-138. Heidelberg: Springer.
  • Faccidomo S, Quadros IM, Takahashi A, Fish EW, Miczek KA (2012) Infralimbic and dorsal raphé microinjection of the 5-HT(1B) receptor agonist CP-93,129: attenuation of aggressive behavior in CFW male mice. Psychopharmacology (Berl). 222(1):117-128.
  • Newman EL, Chu A, Bahamón B, Takahashi A, DeBold JF, Miczek KA (2012) NMDA receptor antagonism: escalation of aggressive behavior in alcohol-drinking mice. Psychopharmacology (Berl). 224(1):167-177.
  • Takahashi A, Quadros IM, de Almeida RM, Miczek KA. (2011) Brain serotonin receptors and transporters: initiation vs. termination of escalated aggression. Psychopharmacology (Berl). 213(2-3):183-212.
  • Miczek KA, Nikulina EM, Takahashi A, Covington HE 3rd, Yap JJ, Boyson CO, Shimamoto A, de Almeida RM (2011) Gene expression in aminergic and peptidergic cells during aggression and defeat: Relevance to violence, depression and drug abuse. Behavior Genetics. 41(6):787-802.
  • Ishii A, Koide T, Takahashi A, Shiroishi T, Hettinger TP, Frank ME, Savoy LD, Formaker BK, Yertutanol S, Lionikas A, Blizard DA (2011) B6-MSM consomic mouse strains reveal multiple loci for genetic variation in sucrose octaacetate aversion. Behavior Genetics. 41(5):716-723.
  • Koide T, Ikeda K, Ogasawara M, Shiroishi T, Moriwaki K, Takahashi A (2011) A new twist on behavioral genetics by incorporating wild-derived mouse strains. Experimental Animals. 60(4): 347-354.
  • Takahashi A, Shimamoto A, Boyson CO, DeBold JF, Miczek KA (2010) GABAB receptor modulation of serotonin neurons in the dorsal raphé nucleus and escalation of aggression in mice. The Journal of Neuroscience. 30(35):11771-11780.
  • Takahashi A, Kwa C, deBold JF, Miczek KA. (2010) GABAA receptors in the dorsal raphé nucleus of mice: escalation of aggression after alcohol consumption. Psychopharmacology (Berl). 211(4):467-477.
  • Takahashi A, Tomihara K, Shiroishi T, Koide T (2010) Genetic mapping of social interaction behavior in B6/MSM consomic mouse strains. Behavior Genetics. 40(3):366-376.
  • Nishi A, Ishii A, Takahashi A, Shiroishi T, Koide T (2010) QTL analysis of measures of mouse home-cage activity using B6/MSM consomic strains. Mammalian Genome. 21(9-10):477-485.
  • Tanaka N, Waki K, Kaneda H, Suzuki T, Yamada I, Furuse T, Kobayashi K, Motegi H, Toki H, Inoue M, Minowa O, Noda T, Takao K, Miyakawa T, Takahashi A, Koide T, Wakana S, Masuya H (2010) SDOP-DB: a comparative standardized-protocol database for mouse phenotypic analyses. Bioinformatics. 26(8):1133-1134.
  • Takahashi A, Yap JJ, Bohager DZ, Faccidomo S, Clayton T, Cook JM, Miczek KA (2009) Glutamatergic and GABAergic modulations of ultrasonic vocalizations during maternal separation distress in mouse pups. Psychopharmacology (Berl). 204(1):61-72.
  • Quadros IM, Takahashi A, Mickzek KA (2009) Serotonin in aggressive and violent behavior. In, Christian Muller & Barry Jacobs (Eds), Handbook of the Behavioral Neurobiology of Serotonin 18 (Chapter 10.4). Philadelphia, USA: Elsevier
  • Takahashi A, Nishi A, Ishii A, Shiroishi T, Koide T (2008) Systematic analysis of emotionality in consomic mouse strains established from C57BL/6J and wild-derived MSM/Ms. Genes Brain and Behavior. 7:849-858.
  • Takahashi A, Shiroishi T, Koide T (2008) Multigenic factors associated with a hydrocephalus-like phenotype found in inter-subspecific consomic mouse strains. Mammalian Genome. 19:333-338.
  • 高橋阿貴、小出剛 (2008)  系統について知ろう(第2章)、マウスの行動を解析しよう(第10章) 小出剛(編)「マウス実験の基礎知識」 オーム社
  • Commentary:Blizard DA, Takahashi A, Galsworthy M, Martin B, Koide T (2007) Test standardization in behavioral neuroscience: a response to Stanford. Journal of Psychopharmacology. 21:136-139.
  • Takahashi A, Kato K, Makino J, Shiroishi T, Koide T (2006) Multivariate analysis of temporal descriptions of open-field behavior in wild-derived mouse strains. Behavior Genetics. 10:1-12.
  • Blizard DA, Wada Y, Onuki Y, Kato K, Mori T, Taniuchi T, Hosokawa H, Otobe T, Takahashi A, Shisa H, Hiai H, Makino J (2005) Use of a standard strain for external calibration in behavioral phenotyping. Behavior Genetics. 35:323-332.
  • Barnes SJ, Hua JM, Pinel JP, Takahashi A, Wig GS (2005) Conditioned effects of kindling three different sites in the hippocampal complex of the rat. Behavioral Neuroscience. 119:1572-1579.
  • 高橋阿貴・加藤克紀・牧野順四郎 (2004) 高・低活動系マウスのオープンフィールド行動の時間構造:ICRおよび近交系5系統との比較 動物心理学研究 54:73-85.
  • Barnes SJ, Magyar O, Pinel JP, Takahashi A. (2004) Anticipating the attack: temporal conditioning during amygdala kindling in rats. Behavioral Neuroscience. 118:89-96.
 
所属学会 日本動物心理学会
日本神経科学会
Society for Neuroscience
International Behavioural and Neural Genetics Society
社会的活動  

 

ページトップにもどる